* 일시 : 11/28(목) 16:30 –
* 연사 : 오지원 교수(연세대학교)
* 장소 : 벤처관 711호
* 제목 : Human embryological lineage tracing study using whole genome sequencing.
*초록
All the somatic cells in a single human individual developed from a single common ancestor cell, the fertilized egg. During pre-implantation development, the mammalian fertilized egg self-organizes into the blastocyst, which includes the inner-cell mass (ICM), giving rise to all human tissues. The cellular organization is a very complex but tightly controlled process and is fundamental to understanding the formation of human bodies, which consists of 10-100 trillion somatic cells. However, cellular dynamics in early embryogenesis, i.e., tracing cellular lineages and fate decisions, has largely remained unexplored, especially in humans, due to both ethical and technical issues.